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Cat. No. |
FER-2611H |
|
Product Overview |
Recombinant
Full-length of human FER (1-822(end) amino acids) was expressed as N
terminal GST-fusion protein (122 kDa) using baculovirus expression
system. GST-FER was purified by using glutathione sepharose
chromatography and anion exchange chromatography. |
|
Description |
Fer protein is a
member of the FPS/FES family of nontransmembrane receptor tyrosine
kinases. It regulates cell-cell adhesion and mediates signaling from
the cell surface to the cytoskeleton via growth factor receptors. |
|
Source |
baculovirus. |
|
Purity |
94 %. The purity
was assessed by SDS-PAGE/CBB staining. |
|
Storage Buffer |
50 mM Tris-HCl, 150
mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5. |
|
ATP |
100
mM.
|
|
Substrate |
Srctide. |
|
Storage |
Store at -80℃.
Avoid repeating freeze-thaws. |
|
Gene Information
|
Gene Name |
FER fer (fps/fes related) tyrosine kinase [ Homo sapiens ] |
|
Synonyms
|
FER; fer (fps/fes
related) tyrosine kinase; TYK3; tyrosine-protein kinase Fer;
p94-Fer; tyrosine kinase 3; phosphoprotein NCP94; proto-oncogene c-Fer;
EC 2.7.10.2 |
|
GeneID |
2241 |
|
mRNA Refseq |
NM_005246 |
|
Protein Refseq |
NP_005237 |
|
MIM |
176942 |
|
UniProt ID |
P16591 |
|
Chromosome Location |
5q21 |
|
Pathway |
Adherens junction |
|
Function |
ATP binding; Rab
GTPase binding; actin binding; cadherin binding; gamma-catenin
binding; non-membrane spanning protein tyrosine kinase activity;
nucleotide binding; protein kinase binding; protein tyrosine kinase
activity; transferase activity |
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