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Cat. No. |
UBD-2640H |
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Product Overview |
Recombinant human
FAT10 was fused at the N-terminus to a His•Tag sequence and
expressed in E. coli. MW = 23342 Da. |
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Description |
FAT10 is a small
ubiquitin-like modifier protein whose expression is synergistically
inducible with γ-interferon and TNF-α. It is composed of two
ubiquitin-like domains and bears a di-glycine motif at the
C-terminus. The wild-type form of FAT10 (but not the di-glycine
form) has been shown to conjugate to target proteins. FAT10
expression also causes apoptosis. |
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Source |
E.coli. |
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Purity |
≥95% by SDS-PAGE. |
|
Form |
Liquid. In 150 mM
NaCl, 20 mM HEPES, 1 mM DTT, 10% glycerol, pH 8.0. Please refer to
vial label for lot-specific concentration.
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Toxicity |
Standard Handling (MSDS
available upon request). |
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Storage |
≤ -70℃.
Avoid freeze/thaw. Following reconstitution, aliquot and freeze
(-70°C). |
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Gene Information
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Gene Name |
UBD ubiquitin D [ Homo sapiens ] |
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Synonyms
|
UBD; ubiquitin D;
FAT10; UBD-3; GABBR1; diubiquitin; ubiquitin-like protein FAT10 |
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GeneID |
10537 |
|
mRNA Refseq |
NM_006398 |
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Protein Refseq |
NP_006389 |
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MIM |
606050 |
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UniProt ID |
O15205 |
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Chromosome Location |
6p21.3 |
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Function |
proteasome binding;
protein binding |
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