|
Cat. No. |
Osm-1771M |
|
Description |
Oncostatin M (OSM) is a cytokine produced by activated T
lymphocytes and macrophages. The biological activities of
OSM are mediated through two types of receptor complexes,
the LIF/OSM shared receptor (type I) and OSM-specific
receptor (OSM-R, type II). |
|
Source |
NSO Cells. |
|
Molecular Weight |
The predicted molecular weight of Recombinant Mouse OSM Rβ
is Mr 109 kDa. However, the actual molecular weight as
observed by migration on SDS Page is Mr >150 kDa. |
|
State Of Matter |
Lyophilized. |
|
Purity |
>90% by SDS Page and analyzed by silver stain. |
|
Endotoxin |
<1.0 EU/µg as determined by the LAL method. |
|
Storage And Stability |
This lyophilized protein is stable for six to twelve months
when stored desiccated at -20°C to -70°C. After aseptic
reconstitution, this protein may be stored at 2°C to 8°C for
one month or at -20°C to -70°C in a manual defrost freezer.
Avoid Repeated Freeze Thaw Cycles. |
|
Gene Information
|
Gene Name |
Osm oncostatin M [ Mus musculus ] |
|
Synonyms |
Osm; oncostatin M; OTTMUSP00000005249 |
|
GeneID |
18413 |
|
mRNA Refseq |
NM_001013365 |
|
Protein Refseq |
NP_001013383 |
|
UniProt ID |
P53347 |
|
Chromosome Location |
11 A1; 11 1.0 cM |
|
Pathway |
Cytokine-cytokine receptor interaction; Jak-STAT signaling
pathway |
|
Function |
cytokine activity |
|
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Abbr.: 
