|
Cat. No. |
Icam2-1746M |
|
Description |
Intercellular
adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of
Differentiation 102), is a member of the intercellular adhesion
molecule (ICAM) family. All ICAM proteins are type I transmembrane
glycoproteins that bind to the leukocyte adhesion LFA-1 protein.
This protein may play a role in lymphocyte recirculation by blocking
LFA-1-dependent cell adhesion. It mediates adhesive interactions
important for antigen-specific immune response, NK-cell mediated
clearance, lymphocyte recirculation, and other cellular interactions
important for immune response and surveillance. |
|
Molecular Weight |
The predicted
molecular weight of Recombinant Mouse ICAM-2 is Mr 49.5 kDa.
However, the actual molecular weight as observed by migration on SDS
Page is Mr 75-80 kDa. |
|
Source |
NSO Cells. |
|
State Of Matter |
Lyophilized. |
|
Purity |
>95% by SDS Page
and analyzed by silver stain. |
|
Endotoxin |
<1.0 EU/µg as
determined by the LAL method. |
|
Storage And
Stability |
This lyophilized
protein is stable for six to twelve months when stored desiccated at
-20℃ to -70℃.
After aseptic reconstitution, this protein may be stored at 2℃
to 8℃ for one
month or at -20℃
to -70℃ in a
manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See
Product Insert for exact lot specific storage instructions. |
|
Gene Information
|
Gene Name |
Icam2 intercellular adhesion molecule 2 [ Mus musculus ] |
|
Synonyms
|
Icam2;
intercellular adhesion molecule 2; CD102; Ly-60; Icam-2;
OTTMUSP00000003460; OTTMUSP00000003463 |
|
GeneID |
15896 |
|
mRNA Refseq |
NM_010494 |
|
Protein Refseq |
NP_034624 |
|
UniProt ID |
P35330 |
|
Chromosome Location |
11 E1; 11 63.0 cM |
|
Pathway |
Cell adhesion
molecules (CAMs); Natural killer cell mediated cytotoxicity |
|
Function |
protein binding |
|
PDB rendering based on 1zxq.
|
Download Datasheet:
|
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Abbr.: 
