|
Cat. No. |
GNRH1-170H |
|
Description |
Gonadotropin-releasing hormone (GNRH), also known as
Luteinizing-hormone releasing hormone (LHRH), is a tropic
peptide hormone responsible for the release of
follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
from the anterior pituitary. These hormones are involved in
reproduction. GNRH is synthesized and released from neurons
within the hypothalamus. Its release can also be regulated
by estrogen. GNRH activity is very low during childhood, and
is activated at puberty. However, once a pregnancy is
established, GNRH activity is not required. GnRH-a are
considered by many clinicians as a clinically useful
co-treatment in chemotherapy. |
|
Source |
Saccharomyces cerevisiae. |
|
Purity |
>95% by SDS Page and HPLC. |
|
Endotoxin |
<0.125 EU/µg. |
|
Biological Activity |
The biological activity is determind by using the Van Hell
Bioasssay described in the British Pharmacopeia. |
|
Storage |
The lyophilized protein should be stored desiccated at -20℃.
The reconstituted protein can be stored for at least one
week at 4℃. For long-term storage of the reconstituted
protein, aliquot into working volumes and store at -20℃in a
manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
|
Gene Information
|
Gene Name |
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing
hormone) [ Homo sapiens ] |
|
Synonyms |
GNRH1; gonadotropin-releasing hormone 1 (luteinizing-releasing
hormone); GRH; GNRH; LHRH; LNRH; gonadotropin-releasing
hormone 1; gonadotropin-releasing hormone 1 (lutienizing
hormone-releasing hormone); Progonadoliberin I;
Progonadoliberin-1; Gonadoliberin-1; Gonadoliberin I;
Luteinizing hormone-releasing hormone I; LH-RH I;
Gonadotropin-releasing hormone I; GnRH-I; Luliberin I;
Gonadorelin; GnRH-associated peptide 1; GnRH-associated
peptide I |
|
GeneID |
2796 |
|
mRNA Refseq |
NM_000825 |
|
Protein Refseq |
NP_000816 |
|
MIM |
152760 |
|
UniProt ID |
P01148 |
|
Chromosome Location |
8p21-p11.2 |
|
Pathway |
GnRH signaling pathway; Neuroactive ligand-receptor
interaction |
|
Function |
gonadotropin hormone-releasing hormone activity |
|
|
Download Datasheet:
|
|
Abbr.: 
