Recombinant Human RAB34, Member RAS Oncogene Family, GST-tagged   [ Back  ]                         Price Inquiry

Cat. No.

RAB34-1110H

Description

Rab34 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small GTPase Rab 34 is restricted to cell surface membrane ruffles and lysosmes. It regulates the spatial distribution of lysosomes and is required for formation of macropinosomes. The GST-Tag facilitates the protein‘s application in typical GST pull-down assays.

Source

E. coli.

Usage

For in vitro use only.

Form

Liquid. Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol.

Activity

100 pmol of protein can bind > 80 pmol of GDP.

Purity

≥ 90% by SDS-PAGE.

Storage

Quality guaranteed for 12 months. Store at -80℃. Avoid freeze / thaw cycles.

Gene Information

Gene Name

RAB34 RAB34, member RAS oncogene family [ Homo sapiens ]

Synonyms

RAB34; RAB34, member RAS oncogene family; Ras-related protein Rab-39; RAH; RAB39; Ras-related protein Rah; OTTHUMP00000163525

GeneID

83871

mRNA Refseq

NM_001142624

Protein Refseq

NP_001136096

MIM

610917

UniProt ID

Q9BZG1

Chromosome Location

17q11.2

Function

GTP binding; GTPase activity; nucleotide binding; guanyl nucleotide binding