Recombinant Rat RAB27A, Member RAS Oncogene Family   [ Back  ]                         Price Inquiry

Cat. No.

Rab27a-1106R

Description

Rab27 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The monomeric GTPase Rab27 subfamily regulates the exocytosis of these cell-specific store organelles. Rab27 acts through organelle-specific effector proteins, such as granuphilin in pancreatic beta cells and melanophilin in melanocytes. The Rab27 and effector complex then interacts with proteins that are essential for membrane transport and fusion.

Source

E. coli.

Usage

For in vitro use only.

Form

Liquid. Supplied in 25 mM HEPES pH 7.2, 200 mM NaCl, 10 mM MgCl2, 10 μM GDP, 2 mM DTE and 10% glycerol.

Activity

100 pmol of protein can bind > 80 pmol of GDP.

Purity

> 90% by SDS-PAGE.

Storage

Quality guaranteed for 12 months, store at -80℃. Avoid freeze / thaw cycles.

Gene Information

Gene Name

Rab27a RAB27A, member RAS oncogene family [ Rattus norvegicus ]

Synonyms

Rab27a; RAB27A, member RAS oncogene family; ram; MGC112618; low Mr GTP-binding protein

GeneID

50645

mRNA Refseq

NM_017317

Protein Refseq

NP_059013

UniProt ID

P23640

Function

GTP binding; myosin V binding; nucleotide binding; protein binding