|
Cat. No. |
RAB11A-1096H |
|
Description |
Rab11A is a
small GTPase that belongs to the Ras superfamily. Rab proteins
play an important role in various aspects of membrane traffic,
including cargo selection, vesicle budding, vesicle motility,
tethering, docking, and fusion. Rab11A is located to Golgi and
recycling endosomes. It facilitates transport from golgi to
apical recycling endosomes and is involved into phagocytosis in
macrophages. |
|
Source |
E. coli. |
|
Usage |
For in vitro
use only. |
|
Form |
Liquid.
Supplied in 20 mM Tris-HCl pH 8.0, 100 mM KCl, 0.2 mM EDTA, 1 mM
DTT and 20% glycerol. |
|
Usage |
For in vitro
use only. |
|
Activity |
100 pmol of
protein can bind > 80 pmol of GDP. |
|
Purity |
> 95% by SDS-PAGE. |
|
Storage |
Quality guaranteed for 12 months,
store at -80°.
Avoid freeze / thaw cycles. |
|
Gene
Information
|
Gene Name |
RAB11A RAB11A, member RAS oncogene family [ Homo sapiens ] |
|
Synonyms
|
RAB11A; RAB11A,
member RAS oncogene family; YL8; MGC1490; RAB 11A, member
oncogene family |
|
GeneID |
8766 |
|
mRNA Refseq |
NM_004663 |
|
Protein Refseq |
NP_004654 |
|
MIM |
605570 |
|
UniProt ID |
P62491 |
|
Chromosome
Location |
15q22.31 |
|
Pathway |
Endocytosis |
|
Function |
GTP binding;
GTPase activity; nucleotide binding; protein binding; syntaxin
binding; transporter activity |
|
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Abbr.: 
