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Cat. No. |
FGF1-199H
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Product
Overview |
Recombinant Human Acidic
Fibroblast Growth Factor
encoding
the mature form of human SOST
(NP_079513.1) (Gln 24- Tyr 213) was expressed fused with a
his tag at the N-terminus. It was produced in E.Coli. |
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Description |
Acidic
fibroblast growth factor (aFGF), also known as
heparin-binding growth factor (HBGF-1) and FGF-1, is a
member of FGF family who are involved in a variety of
biological processes. aFGF is considered to function in
several important physiological and pathological processes,
such as embryonic development, morphogenesis, angiogenesis,
wound healing and atheromatosis. This protein acts as a
mitogen for a variety of mesoderm- and neuroectoderm-derived
cells in vitro and stimulates cell growth, migration, and
differentiation. |
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Molecular
Mass |
The
recombinant human FGF acidic consists of 141 amino acids and
has a calculated molecular mass of 16 Kda as estimated by
SDS-PAGE under reducing conditions. |
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Source |
E.Coli. |
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Predicted N
Terminal |
Met 1. |
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Purity |
﹥98%
as determined by SDS-PAGE. |
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Formulation |
Supplied as
a 0.2μm filtered solution of PBS, pH7.4. |
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Stability |
Samples are
stable for up to twelve months from date of receipt -70oC. |
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Endotoxin |
< 1.0 EU
per 1 μg of the cytokine as determined by the LAL method. |
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Reconstitution |
Follow the
instructions on the vial. Centrifuge the vial at 4℃ before
opening to recover the entire contents. |
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Storage |
Avoid
repeated freeze-thaw cycles. Store it under sterile
conditions at -70℃. It is recommended that the protein be
aliquoted and be used as soon as possible. |
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Gene
Information |
Gene Name |
FGF1 fibroblast growth factor 1 (acidic) [ Homo sapiens ]
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Synonyms
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AFGF; ECGF;
ECGF-beta; ECGFA; ECGFB; FGF-alpha; FGFA; GLIO703; HBGF1;
aFGF; Beta-endothelial cell growth factor; Heparin-binding
growth factor 1 precursor; endothelial cell growth factor,
alpha; FGF-α; HBGF-1; Acidic fibroblast growth factor;
endothelial cell growth factor, beta; fibroblast growth
factor 1 (acidic); heparin-binding growth factor 1; FGF1;
fibroblast growth factor 1 (acidic) |
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GeneID |
2246 |
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mRNA Refseq |
NM_000800 |
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Protein
Refseq |
NP_000791 |
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MIM |
131220 |
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UniProt ID |
P05230 |
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Chromosome
Location |
5q31 |
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Function |
growth
factor activity. heparin binding. protein binding |
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PDB
rendering based on 1afc.
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