|
Cat. No. |
B2M-81H |
|
Product
Overview |
Recombinant
Human
beta-2-microglobulin produced in E.Coli is a non-glycosylated
polypeptide chain having a molecular mass of 11.76kDa. The
rHuB2M is purified by proprietary chromatographic techniques. |
|
Description |
Beta-2-microglobulin is a serum protein found in association
with the major histocompatibility complex (MHC) class I heavy
chain on the surface of nearly all nucleated cells. |
|
Source |
Escherichia
Coli. |
|
Physical
Appearance |
Sterile
Filtered clear solution. |
|
Purity |
Greater than
95.0% as determined by: (a) Analysis by RP-HPLC. (b)
Anion-exchange FPLC. (c) Analysis by reducing and non-reducing
SDS-PAGE Silver Stained. |
|
Formulation |
The sterile
solution (1.1mg/ml) contains phosphate-buffered saline (pH 7.4)
and 0.05% NaN3. |
|
Dimers And
Aggregates |
Less than 1% as
determined by silver stained SDS-PAGE gel analysis. |
|
Endotoxin |
The endotoxin
is less than 0.1 ng/µg of rHuB2M. |
|
Storage |
The rHuB2M
although stable at 4℃
for 3 weeks, should be stored desiccated below -18℃.
For long term storage it is recommended to add a carrier protein
(0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
|
Gene
Information
|
Gene Name |
B2M beta-2-microglobulin [ Homo sapiens ] |
|
Synonyms
|
B2M;
beta-2-microglobulin; Beta-2 microglob ulin form pI 5.3;
beta-2-microglobin; beta chain of MHC class I molecules |
|
GeneID |
567 |
|
mRNA Refseq |
NM_004048 |
|
Protein Refseq |
NP_004039 |
|
UniProt ID |
P61769 |
|
Chromosome
Location |
15q21-q22.2 |
|
MIM |
109700 |
|
Pathway |
Antigen
processing and presentation; HIV Infection; Signaling in Immune
system |
|
Function |
protein binding |
|
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Abbr.: 
