Mouse Anti-Human EPH receptor A1 Monoclonal Antibody   [ Back  ]                         Price Inquiry

Cat. No.

CAB184

Description

EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and it also can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.

Synonyms

EPHA1; EPH; EPHT; EPHT1; MGC163163; EPH receptor A1; ephrin receptor EphA1; oncogene EPH; eph tyrosine kinase 1; soluble EPHA1 variant 1; soluble EPHA1 variant 2; ephrin type-A receptor 1; tyrosine-protein kinase receptor EPH; erythropoietin-producing hepatoma amplified sequence; EC 2.7.10.1; EphA1; MGC163163.

Immunogen

Ni-NTA purified truncated recombinant EphA1 expressed in E. Coli strain BL21 (DE3).

Species

Human

Isotype

IgG1

Application

Western Blot: 1: 200- 1: 1,000. IHC(P): 1: 200- 1: 1,000. IHC(F): 1: 200- 1: 1,000. ELISA: Propose dilution 1: 10,000. Determining optimal working dilutions by titration test.

Formulation

Antibodies are purified by protein A affinity chromatography.

Storage

-20℃