|
Cat. No. |
YWHAG-100H |
|
Product
Overview |
Recombinant
Human 14-3-3
gamma comprises a 246 amino acid fragment (2-247) corresponding
to the 14-3-3 gamma coding sequence and is expressed in E. coli
with an amino-terminal hexahistidine tag. |
|
Description |
14-3-3 is a
general name given to a family of acidic, soluble, ubiquitously
expressed 28kDa proteins that are the products of related but
separate genes. They are considered isoforms and are named eta
(η), gamma (γ), delta/zeta (δ/ξ), alpha/beta (α/β), theta/tau
(θ/τ), sigma (σ) or epsilon (ε). Interactions are generally
mediated by phosphorylation of specific binding sites in the
target proteins. |
|
Source |
E.coli. |
|
Purity |
>95% by SDS-PAGE |
|
Form |
Liquid |
|
Storage |
Store at 4°C if
entire vial will be used within 2-4 weeks. Store, frozen at
-20°C for longer periods of time. Please avoid freeze thaw
cycles. |
|
Gene
Information
|
Gene Name |
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
activation protein, gamma polypeptide [ Homo sapiens ] |
|
Synonyms
|
14-3-3 protein
gamma; Protein kinase C inhibitor protein 1; KCIP-1; YWHAG;
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein; gamma polypeptide; MGC111427; MGC126532; MGC138156;
OTTHUMP00000165851; OTTHUMP00000165852; OTTHUMP00000165854;
OTTHUMP00000165858; OTTHUMP00000165859; OTTHUMP00000165860;
14-3-3 protein/cytosolic phospholipase A2; 14-3-3 zeta;
phospholipase A2; tyrosine 3-monooxygenase/tryptophan
5-monooxygenase activation protein, zeta polypeptide; YWHAZ. |
|
GeneID |
7532 |
|
mRNA Refseq |
NM_012479 |
|
Protein Refseq |
NP_036611 |
|
MIM |
605356 |
|
UniProt ID |
P61981 |
|
Chromosome
Location |
7q11.23 |
|
Pathway |
Cell cycle;
Cell Cycle, Mitotic |
|
Function |
insulin-like
growth factor receptor binding; protein domain specific binding;
protein kinase C binding; protein kinase C inhibitor activity |
|

PDB rendering based on 2b05.
Available structures:
2b05
|
Download Datasheet:

|
|