Recombinant Human Androgen receptor   [ Back  ]                         Price Inquiry

Cat. No.

CRY18

Product Overview

Recombinant Human AR produced in E.coli is a single non-glycosylated polypeptide chain containing 250 amino acids and having a molecular mass of approximately 29 kDa.

Description

Androgen receptor (AR) is a ligand-inducible steroid hormone receptor that mediates androgen action, determining male sexual phenotypes and promoting spermatogenesis. As the androgens play a dominant role in male sexual development and function, steroidal androgen agonists have been used clinically for some years. However, there is a risk of potential side effects and most steroidal androgens cannot be dosed orally, which limits the use of these substances. 1,2-Dihydro-6-N,N-bis(2,2,2-trifluoroethyl)amino-4-trifluoromethyl-2-quinolinone (LGD2226) is a synthetic nonsteroidal ligand and a novel selective AR modulator.

Synonyms

RP11-383C12.1; AIS, DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM; OTTHUMP00000023450; OTTHUMP00000061928; dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; spinal and bulbar muscular atrophy

Source

E.coli

Physical Appearance

Sterile Liquid

Purity

>98% as determined by RP-HPLC and SDS-PAGE .

Storage

Store at -80°C. Aliquot to avoid repeated freezing and thawing.

Reconstitution

Sample is ready to use.  Centrifuge the vial at 4°C before openting to recover the entire contents.