Recombinant Human Extracellular fragment of Fc alpha Receptor I (CD89)   [ Back  ]                         Price Inquiry

Cat. No.

CRY04

Product Overview

Recombinant Human  produced in E.coli is a single non-glycosylated polypeptide chain containing 218 amino acids and having a molecular mass of approximately 25 kDa.

Description

Human FcalphaRI (CD89) is the receptor specific for IgA, an immunoglobulin that is abundant in mucosa and is also found in high concentrations in serum. Although FcalphaRI is an immunoglobulin Fc receptor (FcR), it differs in many ways from FcRs for other immunoglobulin classes. The genes of most FcRs are located on chromosome 1 at 1q21-23, whereas FcalphaRI is on chromosome 19, at 19q13.4, a region called the leukocyte receptor complex, because it is clustered with several leukocyte receptor families including killer cell inhibitory receptors (KIRs) and leukocyte Ig-like receptors (LIRs). The amino acid sequence of FcalphaRI shares only 20% homology with other FcRs but it has around 35% homology with its neighboring LIRs and KIRs.

Synonyms

FCAR; XXbac-BPG230H20.5, CD89; Fc alpha receptor; IgA Fc receptor; OTTHUMP00000068692; OTTHUMP00000068696; OTTHUMP00000068697; OTTHUMP00000068698; CD89; CD89 antigen; Fc receptor; Fc fragment of IgA, receptor; IgA Fc receptor

Source

E.coli

Physical Appearance

Sterile liquid.

Purity

>98% as determined by RP-HPLC and SDS-PAGE .

Storage

Store at -80°C. Aliquot to avoid repeated freezing and thawing.

Reconstitution

Sample is ready to use.  Centrifuge the vial at 4°C before openting to recover the entire contents.