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   Diagnostic Antigen >> hCG-b

   Human Chorionic Gonadotropin beta   [ Back  ]                         Price Inquiry

Cat. No.

CDA015

Description

Human chorionic gonadotropin (hCG) is a peptide hormoneproduced in pregnancy, that is made by the embryosoon after conceptionand later by the syncytiotrophoblast(part of the placenta). Its role is to prevent the disintegration of the corpus luteumof the ovaryand thereby maintain progesteroneproduction that is critical for a pregnancyin humans. hCG may have additional functions, for instance it is thought that it affects the immune tolerance of the pregnancy. Early pregnancy testinggenerally is based on the detection or measurement of hCG.

Source

Human Pregnancy Urine

Format

Purified, Lyophilized. Reconstitute to 1mg/ml in 0.15M Potassium Phosphate. Prior to reconstitution rap the bottom of the vial against a bench top to ensure all product is at the bottom of the vial. Allow the reconstitution buffer to equilibrate to room temperature before use. Allow the vial to sit without agitation for at least 5 minutes followed by vortexing at slow speed or gentle swirling.

Contaminants

whole hCG   0.9%                (Abbott IMX)

hFSH       <detectable limit       (Abbott IMX)

hTSH       <detectable limit       (Bayer ACS180)

hLH        0.002%               (Abbott IMX)

hPRL       <detectable limit       (Bayer ACS180)

Purification

≥80% pure (SDS-PAGE).

Buffer

Lyophilized from 50mM Ammonium bicarbonate

Applications

Specific methodologies have not been tested using this product.

Storage

Store lyophilized product at -20℃. After reconstitution, aliquot and store at  -20℃. Avoid multiple freeze/thaw cycles.

Warnings

All human source materials have tested negative for HIV 1, HIV 2, HCV, Hepatitis A antibodies and HBsAg and HIV Antigen. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.

Gene Information

Gene Name

CGB

Synonyms

Chorionic gonadotropin beta polypeptide; CGB3; CGB5; CGB7; CGB8; hCGB; Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit; chorionic gonadotropin, beta polypeptide. CGHB_HUMAN; Choriogonadotropin subunit beta [Precursor].

GeneID

1082

mRNA Refseq

NM_000737

Protein Refseq

NP_000728

MIM

118860

UniProt ID

P01233

Chromosome Location

19q13.32

Function

hormone activity.



PDB rendering based on 1hcn.
Available structures: 1hcnn, 1hrp, 1qfw


 

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