|
Cat. No. |
CAB365
|
|
Antigen
Information |
This gene is a
member of the EPO/TPO family and encodes a secreted,
glycosylated cytokine composed of four alpha helical bundles.
The protein is found in the plasma and regulates red cell
production by promoting erythroid differentiation and initiating
hemoglobin synthesis. This protein also has neuroprotective
activity against a variety of potential brain injuries and
antiapoptotic functions in several tissue types. |
|
Immunogen |
r.Human
erythropoietin. |
|
Ig Subclass |
Mouse IgG1. |
|
Purification
Method |
Ion exchange. |
|
Protein
Concentration |
1mg/ml in PBS
(after reconstitution). |
|
Shipping
Conditions |
Antibody is
shipped lyophilized at ambient temperature. |
|
Applications |
Direct ELISA,
Western Blot, Immuneprecipitation. |
|
Antibody
Properties |
Staining
antibody. For staining, use 10 µl/106 cells. This antibody
recognizes human thymocytes. |
|
Reconstitution |
Reconstitute
with 0.5ml of H2O. Mix gently, wash the sides of the vial and
wait 30-60 seconds before use. |
|
Titer |
By direct
ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline
phosphatase conjugated rabbit anti-mouse Ig (Jackson
Laboratories). |
|
Stability /
Shelf Life |
Two years lyophilized, one month in
solution at 4℃. |
|
Storage
Procedures |
Lyophilized: store at 4℃. After
reconstitution, if not intended for use within a month, aliquot
and store at
‑20℃. |
|
Gene
Information
|
Gene Name |
EPO erythropoietin [ Homo sapiens ] |
|
Synonyms
|
EPO;
erythropoietin; EP; MVCD2; MGC138142; ENSG00000130427 |
|
GeneID |
2056 |
|
mRNA Refseq |
NM_000799 |
|
Protein Refseq |
NP_000790 |
|
MIM |
133170 |
|
UniProt ID |
P01588 |
|
Chromosome
Location |
7q21 |
|
Pathway |
Cytokine-cytokine receptor interaction; Hematopoietic cell
lineage; Jak-STAT signaling pathway |
|
Function |
JAK pathway
signal transduction adaptor activity; erythropoietin receptor
binding; hormone activity; protein binding |
|
|
Download Datasheet:
|
|
Abbr.: 
