Mouse PRDX2 Monoclonal Antibody   [ Back  ]                         Price Inquiry

Cat. No.

CAB028

Antigen information

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.

Immunogen

Mixed immunization with His-tagged ABCC2 (1366-1545aa), His-tagged PRDX2 (1-192aa), His-tagged PRDX3 (80-257aa) and His-tagged PRDX4 (98-271aa).

Specificity

Recognizes recombinant PRDX2 (Homo sapiens peroxiredoxin 2) at the molecular weight of 38kDa.

Clone

UDF012

Species Cross-reactivity

Human. Others not determined.

Formulation

200μg of protein G purified polyclonal antibody in storage buffer (0.1M Tris-HCl, pH 7.4, 0.15M NaCl, 0.04% merthiolate) and 50% glycero

Handling Recommendations

Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications

This antibody is effective in ELISA, and immunoblotting for both tagged and native proteins.

Recommended Working Dilution

The optimal working dilution should be determined according to each specific assay condition.

Gene Information

Gene Name

PRDX2  

Synonyms

PRDX2; PRP; MGC4104; NKEFB; PRXII; TDPX1; TSA; peroxiredoxin 2; torin; thioredoxin peroxidase 1;  thiol-specific antioxidant 1; natural killer-enhancing factor B; thioredoxin-dependent peroxide reductase 1

GeneID

7001

mRNA Refseq

NM_181737

Protein Refseq

NP_859427

UniProt ID

P32119

Chromosome Location

19p13.2

Function

antioxidant activity; oxidoreductase activity; thioredoxin peroxidase activity.