Mouse FTL Monoclonal Antibody   [ Back  ]                         Price Inquiry

Cat. No.

CAB016

Antigen information

FTL encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains.Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome.This gene has multiple pseudogenes.  

Isotope

Mouse Monoclonal IgG1κ

Immunogen

Cytosolic proteins of human adult liver tissues (fraction 3)

Applications

This antibody is effective in ELISA and Western blot assay.

Specificity

Recognizes fusion FTL (Homo sapiens ferritin, light polypeptide) protein at the molecular weight of 24 kDa.

Species Cross-reactivity

Human. Others not determined.

Formulation

200μg of protein G purified IgG1κ in 172μL of 70% storage buffer (0.1M Tris-HCl, pH 7.4, 0.15M NaCl, 0.04% merthiolate) and 30% glycerol.

Handling Recommendations

Aliquot into microcentrifuge tubes and stored at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Recommended Working Dilution

The optimal working dilution should be determined according to each specific assay condition.  

Gene Information

Gene Name

FTL

Synonyms

MGC71996; FTL; ferritin, light polypeptide; ferritin, light polypeptide; L apoferritin; ferritin L-chain; ferritin L subunit; ferritin light chain; ferritin light polypeptide-like 3; FTL

GeneID

2512

mRNA Refseq

NM_000146

Protein Refseq

NP_000137

UniProt ID

P02792

MIM

134790

Chromosome Location

19q13.3-q13.4; 19q13.3

Function

ferric iron binding; identical protein binding; oxidoreductase activity