Mouse ALB Monoclonal Antibody   [ Back  ]                         Price Inquiry

Cat. No.

CAB004

Antigen information

Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.

Immunogen

Cytosolic proteins of human adult liver tissues (fraction 10).

Species Cross-reactivity

Human. Others not determined.

Formulation

200μg of protein G purified IgG1κ in 172μL of 70% storage buffer (0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.04% merthiolate) and 30% glycerol.

Handling Recommendations

Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Recommended Working Dilution

The optimal working dilution should be determined according to each specific assay condition.

Applications

This antibody is effective in ELISA and Western blot.

Specificity

Recognizes ALB (Homo sapiens albumin) at 75, 66, 40 kDa in the lysates of human liver tissues.

Gene Information

Gene Name

ALB

Synonyms

ALB; DKFZp779N1935; PRO0883; PRO0903; PRO1341; albumin; serum albumin; growth-inhibiting protein 20; cell growth inhibiting protein 42

GeneID

213

mRNA Refseq

NM_000477

Protein Refseq

NP_000468

MIM

103600

UniProt ID

P02768

Chromosome Location

4q11-q13

Pathway

Hemostasis; Lipid and lipoprotein metabolism.

Function

DNA binding; antioxidant activity; copper ion binding; drug binding; fatty acid binding; metal ion binding; contributes_to oxygen binding; protein binding; pyridoxal phosphate binding; toxin binding.