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Cat. No. |
CDA094P |
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Product
Overview |
Recombinant
Human CD-105 protein 26-176 a.a. expressed in E.coli,
43 kDa. |
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Description |
CD105 or Endoglin or GP160 is a
Type I transmembrane protein, which is
highly expressed on human vascular endothelial cells. It exists
as an O- and N-glycosylated homodimer. Up-regulation of endoglin
expression has been demonstrated in tumor vasculature and
proliferating cells, suggesting that it is a
proliferation-associated endothelial cell marker. CD105 binds to
TGFBeta1 and Beta3 with high affinity but not TGF-Beta2. |
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Synonyms |
ENG; CD105;
END; FLJ41744; HHT1; ORW; ORW1; endoglin; CD105 antigen;
OTTHUMP00000022221; Osler-Rendu-Weber syndrome 1. |
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Source |
E.coli |
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Presentation |
Recombinant
Human CD-105 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5,
1mM EDTA and 20% Glycerol. |
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Applications |
•ELISA
•Inhibition
Assays •Western
Blotting |
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Characterization |
On SDS-PAGE
commassie blue stained gel, the purified recombinant protein
shows a band at 43 kDa. |
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Storage |
Store vial at
-20℃ to -80℃.
When stored at the recommended temperature, this protein is
stable for 12 months. |
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Download Datasheet:
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Abbr.: 
